Find Research Outputs

2017

3D Stacked Construct: A Novel Substitute for Corneal Tissue Engineering

Shrestha, P., Nicholas, S. E. & Karamichos, D. Apr 28 2017 In : Methods in Molecular Biology.

Research output: Contribution to journalArticle

Tissue Engineering
Sphingolipids
Corneal Injuries
Cornea
Lipids

Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinases

Ding, H., Zhang, G., Sin, K. W. T., Liu, Z., Lin, R. K., Li, M. & Li, Y. P. Apr 1 2017 In : AMB Express.

Research output: Contribution to journalArticle

Activins
Mitogen-Activated Protein Kinases
Skeletal Muscle
Muscles
Skeletal Muscle Fibers

Acute hypoxia influences collagen and matrix metalloproteinase expression by human keratoconus cells in vitro.

McKay, T. B., Hjortdal, J., Shrestha, P. & Karamichos, D. Apr 20 2017 In : PLoS One.

Research output: Contribution to journalArticle

Keratoconus
Matrix Metalloproteinases
Anoxia
Collagen
In Vitro Techniques

Adams–Oliver syndrome review of the literature: Refining the diagnostic phenotype

Hassed, S., Li, S., Mulvihill, J., Aston, C. & Palmer, S. Mar 1 2017 In : American Journal of Medical Genetics, Part A. 173, 3, p. 790-800 11 p.

Research output: Contribution to journalReview article

Phenotype
Blood Vessels
Central Nervous System
Nervous System Malformations
Ectodermal Dysplasia

Adipose Stromal Cells from Visceral and Subcutaneous Fat Facilitate Migration of Ovarian Cancer Cells via IL-6/JAK2/STAT3 Pathway.

Kim, B., Kim, H. S., Kim, S., Tsang, B. K., Dhanasekaran, D. & Song, Y. H. Apr 1 2017 In : Cancer Research and Treatment. 49, 2, p. 338-349 11 p.

Research output: Contribution to journalArticle

Intra-Abdominal Fat
Stromal Cells
Ovarian Neoplasms
Interleukin-6
Conditioned Culture Medium

A Dominant Mutation in Rpe65, D477G, Delays Dark Adaptation and Disturbs the Visual Cycle in the Mutant Knock-In Mice

Shin, Y., Moiseyev, G., Chakraborty, D. & Ma, J. X. Mar 1 2017 In : American Journal of Pathology. 187, 3, p. 517-527 11 p.

Research output: Contribution to journalArticle

Dark Adaptation
Mutation
Retinitis Pigmentosa
Regeneration
Leber Congenital Amaurosis

Advancing viral RNA structure prediction: Measuring the thermodynamics of pyrimidine-rich internal loops

Phan, A., Mailey, K., Saeki, J., Gu, X. & Schroeder, S. J. May 1 2017 In : RNA. 23, 5, p. 770-781 12 p.

Research output: Contribution to journalArticle

Viral Structures
Viral RNA
Thermodynamics
RNA
Ribosomes
2 Citations

AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization

Bastian, A., Matsuzaki, S., Humphries, K. M., Pharaoh, G. A., Doshi, A., Zaware, N., Gangjee, A. & Ihnat, M. Mar 1 2017 In : Cancer Letters. p. 149-157 8 p.

Research output: Contribution to journalArticle

Anoxia
Neoplasms
Oxygen Consumption
Mitochondria
Pyruvate Kinase

A laparoscopic applicator probe for real-time en-face mapping of near-surface optical sources of heterogeneity over a 1cm instrument-tip-size field-of-view

Piao, D., Bartels, K. E., Holyoak, G. R. & Patel, S. 2017 Molecular-Guided Surgery: Molecules, Devices, and Applications III. SPIE, Vol. 10049, 1004917

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Library Catalogs
probes
Tissue
Edema Disease of Swine
field of view

Altered populations of natural killer cells, cytotoxic T lymphocytes, and regulatory T cells in major depressive disorder: Association with sleep disturbance

Suzuki, H., Savitz, J., Kent Teague, T., Gandhapudi, S. K., Tan, C., Misaki, M., McKinney, B. A., Irwin, M. R., Drevets, W. C. & Bodurka, J. Mar 15 2017 In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

Major Depressive Disorder
Cytotoxic T-Lymphocytes
Regulatory T-Lymphocytes
Natural Killer Cells
Sleep

A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC).

Sandoval, I. T., Delacruz, R. G., Miller, B. N., Hill, S., Olson, K. A., Boyd, K., Satterfield, C., Remmen, H. V., Rutter, J. & Jones, D. Apr 11 2017 In : eLife.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Pyruvic Acid
Metabolism
Blood Flow Velocity
Zebrafish

A method for safely resecting anterior butterfly gliomas: The surgical anatomy of the default mode network and the relevance of its preservation

Burks, J. D., Bonney, P. A., Conner, A. K., Glenn, C. A., Briggs, R. G., Battiste, J. D., McCoy, T., O'Donoghue, D. L., Wu, D. H. & Sughrue, M. E. Jun 1 2017 In : Journal of Neurosurgery. 126, 6, p. 1795-1811 17 p.

Research output: Contribution to journalArticle

Butterflies
Glioma
Anatomy
Incidence
Akinetic Mutism

A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases

Zhao, J. , Ma, J. , Deng, Y. , Kelly, J. A. , Kim, K. , Bang, S. Y. , Lee, H. S. , Li, Q. Z. , Wakeland, E. K. , Qiu, R. , Liu, M. , Guo, J. , Li, Z. , Tan, W. , Rasmussen, A. , Lessard, C. J. , Sivils, K. L. , Hahn, B. H. , Grossman, J. M. , Kamen, D. L. & 5 others Gilkeson, G. S., Bae, S. C., Gaffney, P. M., Shen, N. & Tsao, B. P. Mar 1 2017 In : Nature Genetics. 49, 3, p. 433-437 5 p.

Research output: Contribution to journalArticle

Autoimmune Diseases
Odds Ratio
Systemic Lupus Erythematosus
Reactive Oxygen Species
Interferon Type I

Analysis of Preoperative Metabolic Risk Factors Affecting the Prognosis of Patients with Esophageal Squamous Cell Carcinoma: The Fujian Prospective Investigation of Cancer (FIESTA) Study

Peng, F., Hu, D., Lin, X., Chen, G., Liang, B., Zhang, H., Dong, X., Lin, J., Zheng, X. & Niu, W. Feb 1 2017 In : EBioMedicine. 16, p. 115-123 9 p.

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
Neoplasms
Epithelial Cells
Mortality
Esophageal Neoplasms

Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

Qi, H., Priyadarsini, S., Nicholas, S. E., Sarker-Nag, A., Allegood, J., Chalfant, C. E., Mandal, N. A. & Karamichos, D. Apr 2017 In : Journal of Lipid Research. 58, 4, p. 636-648 13 p.

Research output: Contribution to journalArticle

Keratoconus
Sphingolipids
Fibroblasts
Ceramides
Sphingosine

A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse

Deepa, S. S., Bhaskaran, S., Espinoza, S., Brooks, S. V., McArdle, A., Jackson, M. J., Van Remmen, H. & Richardson, A. Apr 1 2017 In : GeroScience. 39, 2, p. 187-198 12 p.

Research output: Contribution to journalArticle

Knockout Mice
Superoxide Dismutase
Sarcopenia
Cell Aging
Geriatrics
2 Citations

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1−/− mice is correlated to increased cellular senescence

Zhang, Y., Unnikrishnan, A., Deepa, S. S., Liu, Y., Li, Y., Ikeno, Y., Sosnowska, D., Van Remmen, H. & Richardson, A. Apr 1 2017 In : Redox Biology. 11, p. 30-37 8 p.

Research output: Contribution to journalArticle

Cell Aging
Oxidative Stress
Phenotype
Oxidoreductases Acting on CH-NH Group Donors
Castration

An extension of Kish's formula for design effects to two- and three-stage designs with stratification

Chen, S. & Rust, K. Jun 1 2017 In : Journal of Survey Statistics and Methodology. 5, 2, p. 111-130 20 p., smw036

Research output: Contribution to journalArticle

effect
Design effect
correlation
survey
data

Annexin-directed β-glucuronidase for the targeted treatment of solid tumors

Guillen, K. P., Ruben, E. A., Virani, N. & Harrison, R. G. Feb 1 2017 In : Protein Engineering, Design and Selection. 30, 2, p. 85-94 10 p.

Research output: Contribution to journalArticle

Annexins
Glucuronidase
Neoplasms
Proteins
Fusion reactions

Annexin-directed β-glucuronidase for the targeted treatment of solid tumors.

Guillen, K. P., Ruben, E. A., Virani, N. & Harrison, R. Feb 1 2017 In : Protein Engineering, Design and Selection. 30, 2, p. 85-94 9 p.

Research output: Contribution to journalArticle

Annexins
Glucuronidase
Neoplasms
Proteins
Fusion reactions

An Open-Source Automated Peptide Synthesizer Based on Arduino and Python

Gali, H. Jan 1 2017 In : SLAS Technology.

Research output: Contribution to journalArticle

Boidae
Peptides
Amino Acids

A novel homozygous VPS45 p.P468L mutation leading to severe congenital neutropenia with myelofibrosis

Shah, R. K., Munson, M., Wierenga, K. J., Pokala, H. R., Newburger, P. E. & Crawford, D. 2017 In : Pediatric Blood and Cancer.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Neutropenia
Mutation
Membrane Fusion
Extramedullary Hematopoiesis

A novel monoclonal antibody against the von Willebrand Factor A2 domain reduces its cleavage by ADAMTS13

Zhang, L., Su, J., Shen, F., Ma, Z., Zhao, Y., Xia, L. & Ruan, C. Feb 6 2017 In : Journal of Hematology and Oncology. 10, 1, p. 1-4 4 p.

Research output: Contribution to journalLetter

von Willebrand Factor
varespladib methyl
Proteolysis
Molecular Weight
Monoclonal Antibodies

A novel nonsense NBEAL2 gene mutation causing severe bleeding in a patient with gray platelet syndrome

Cao, L., Su, J., Li, J., Yu, Z., Bai, X., Wang, Z., Xia, L. & Ruan, C. May 13 2017 In : Platelets. p. 1-4 4 p.

Research output: Contribution to journalArticle

Gray Platelet Syndrome
Nonsense Codon
Blood Platelets
Hemorrhage
Mutation

Antibiotic prophylaxis for surgical site infections as a risk factor for infection with Clostridium difficile

Balch, A., Wendelboe, A. M., Vesely, S. K. & Bratzler, D. W. Jun 1 2017 In : PLoS ONE. 12, 6, e0179117

Research output: Contribution to journalArticle

Antibiotic Prophylaxis
Clostridium difficile
Anti-Bacterial Agents
Infection
antibiotics

Antitumor Synergism and Enhanced Survival with a Tumor Vasculature-Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide.

Krais, J. J., Virani, N., McKernan, P. H., Nguyen, Q., Fung, K-M., Sikavitsas, V., Kurkjian, C. & Harrison, R. May 18 2017 In : Molecular Cancer Therapeutics.

Research output: Contribution to journalArticle

Prodrugs
Sirolimus
Cyclophosphamide
Enzymes
Neoplasms

Anxiety and cannabis-related problem severity among dually diagnosed outpatients: The impact of false safety behaviors

Buckner, J. D., Zvolensky, M. J., Ecker, A. H., Jeffries, E. R., Lemke, A. W., Dean, K. E., Businelle, M. S. & Gallagher, M. W. Jul 1 2017 In : Addictive Behaviors. 70, p. 49-53 5 p.

Research output: Contribution to journalArticle

Cannabis
Outpatients
Anxiety
Safety
Anxiety Disorders

A pharmacokinetic/pharmacodynamic model of ACE inhibition of the renin-angiotensin system for normal and impaired renal function

Ford Versypt, A. N., Harrell, G. K. & McPeak, A. N. Sep 2 2017 In : Computers and Chemical Engineering. 104, p. 311-322 12 p.

Research output: Contribution to journalArticle

Anthralin
Enzymes
Pharmacodynamics
Forearm
Pharmacokinetics

A phase I pharmacokinetic study of intraperitoneal bortezomib and carboplatin in patients with persistent or recurrent ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study

Jandial, D. A., Brady, W. E., Howell, S. B., Lankes, H. A., Schilder, R. J., Beumer, J. H., Christner, S. M., Strychor, S., Powell, M. A., Hagemann, A. R., Moore, K. N., Walker, J. L., DiSilvestro, P. A., Duska, L. R., Fracasso, P. M. & Dizon, D. S. May 1 2017 In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Carboplatin
Ovarian Neoplasms
Pharmacokinetics
Area Under Curve
Proteasome Inhibitors

A phase I trial of paclitaxel, cisplatin, and veliparib in the treatment of persistent or recurrent carcinoma of the cervix: An NRG Oncology Study (NCT#01281852)

Thaker, P. H., Salani, R., Brady, W. E., Lankes, H. A., Cohn, D. E., Mutch, D. G., Mannel, R. S., Bell-McGuinn, K. M., Di Silvestro, P. A., Jelovac, D., Carter, J. S., Duan, W., Resnick, K. E., Dizon, D. S., Aghajanian, C. & Fracasso, P. M. 2017 In : Annals of Oncology. 28, 3, p. 505-511 7 p.

Research output: Contribution to journalArticle

Paclitaxel
Cervix Uteri
Cisplatin
Carcinoma
Confidence Intervals

Applying a deep learning based CAD scheme to segment and quantify visceral and subcutaneous fat areas from CT images

Wang, Y., Qiu, Y., Thai, T., Moore, K., Liu, H. & Zheng, B. 2017 Medical Imaging 2017: Computer-Aided Diagnosis. SPIE, Vol. 10134, 101343G

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Intra-Abdominal Fat
Learning
Oils and fats
fats
Fats
Ovarian Neoplasms
Tomography
Drug Therapy
ROC Curve
Neoplasms

Apply radiomics approach for early stage prognostic evaluation of ovarian cancer patients: A preliminary study

Danala, G., Wang, Y., Thai, T., Gunderson, C., Moxley, K., Moore, K., Mannel, R., Liu, H., Zheng, B. & Qiu, Y. 2017 Medical Imaging 2017: Computer-Aided Diagnosis. SPIE, Vol. 10134, 1013449

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ovarian Neoplasms
Neoplasms
tumors
Contraception Behavior
Tumors

APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases

Nguyen, C. B., Houchen, C. W. & Ali, N. Feb 1 2017 In : Experimental Biology and Medicine. 242, 3, p. 242-249 8 p.

Research output: Contribution to journalReview article

Neoplastic Stem Cells
Liver Diseases
Phosphotransferases
Fibrin
Supravalvular Aortic Stenosis

A simplified method of accurate postprocessing of diffusion tensor imaging for use in brain tumor resection

Bonney, P. A., Conner, A. K., Boettcher, L. B., Cheema, A. A., Glenn, C. A., Smitherman, A. D., Pittman, N. A. & Sughrue, M. E. 2017 In : Operative Neurosurgery. 13, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Brain Neoplasms
Neoplasms
Neuronavigation
Glioma

A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection

Niu, X., Brahmbhatt, H., Mergenthaler, P., Zhang, Z., Sang, J., Daude, M., Ehlert, F. G. R., Diederich, W. E., Wong, E., Zhu, W., Pogmore, J., Nandy, J. P., Satyanarayana, M., Jimmidi, R. K., Arya, P., Leber, B., Lin, J., Culmsee, C., Yi, J. & Andrews, D. W. Apr 20 2017 In : Cell Chemical Biology. 24, 4, p. 493-506 13 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Cell Death
Oligomerization
Molecules
Apoptosis

Assessment of fracture risk in proximal tibia with tumorous bone defects by a finite element method.

Lin, Y., Ma, L., Zhu, Y., Lin, Z., Yao, Z., Zhang, Y. & Mao, C. May 27 2017 In : Microscopy Research and Technique.

Research output: Contribution to journalArticle

tibia
defects
Tibia
Bone and Bones
Defects

Association between breath alcohol concentration and waterpipe lounge patrons’ carbon monoxide exposure: A field investigation

Leavens, E. L., Brett, E. I., Frank, S., Shaikh, R. A., Leffingwell, T. R., Croff, J. M. & Wagener, T. L. Jan 1 2017 In : Drug and Alcohol Dependence. 170, p. 152-155 4 p.

Research output: Contribution to journalArticle

Carbon Monoxide
Alcohols
Smoking
Alcohol Drinking
Smoke

Association between daily walking and antioxidant capacity in patients with symptomatic peripheral artery disease

Gardner, A. W., Montgomery, P. S., Zhao, Y. D., Silva-Palacios, F., Ungvari, Z., Csiszar, A. & Sonntag, W. E. Jun 1 2017 In : Journal of Vascular Surgery. p. 1762-1768 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Walking
Antioxidants
Hydroxyl Radical
Ankle Brachial Index

Association Between Maternal Stress, Work Status, Concern About Child Weight, and Restrictive Feeding Practices in Preschool Children.

Swyden, K., Sisson, S., Morris, A., Lora, K., Weedn, A. E., Copeland, K. A. & DeGrace, B. Jun 1 2017 In : Maternal and Child Health Journal. 21, 6, p. 1349-1357 8 p.

Research output: Contribution to journalArticle

Maternal Welfare
Pediatric Obesity
Child Welfare
Linear Models
Analysis of Variance

Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis

Munroe, M. E., Pezant, N., Brown, M. A., Fife, D. A., Guthridge, J. M., Kelly, J. A., Wiley, G., Gaffney, P. M., James, J. A. & Montgomery, C. G. Feb 1 2017 In : PLoS ONE. 12, 2, e0171193

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
lupus erythematosus
Hexosaminidase A
Interleukin-6
interleukin-6

A state-of-the-art review and guidelines for tumor treating fields treatment planning and patient follow-up in glioblastoma

Trusheim, J., Dunbar, E., Battiste, J., Iwamoto, F., Mohile, N., Damek, D., Bota, D. A. & Connelly, J. Jan 1 2017 In : CNS oncology. p. 29-43 24 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Physiologic Monitoring
Patient Safety
Brain Neoplasms

A stratified randomized double-blind phase II trial of celecoxib for treating patients with cervical intraepithelial neoplasia: The potential predictive value of VEGF serum levels: An NRG Oncology/Gynecologic Oncology Group study

Rader, J. S., Sill, M. W., Beumer, J. H., Lankes, H. A., Benbrook, D. M., Garcia, F., Trimble, C., Tate Thigpen, J., Lieberman, R., Zuna, R. E., Leath, C. A., Spirtos, N. M., Byron, J., Thaker, P. H., Lele, S. & Alberts, D. May 1 2017 In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Cervical Intraepithelial Neoplasia
Vascular Endothelial Growth Factor A
Serum
Placebos
Biopsy

A three-dimensional in vitro model to demonstrate the haptotactic effect of monocyte chemoattractant protein-1 on atherosclerosis-associated monocyte migration

Ghousifam, N., Mortazavian, H., Bhowmick, R., Vasquez, Y., Blum, F. D. & Gappa-Fahlenkamp, H. Apr 1 2017 In : International Journal of Biological Macromolecules. 97, p. 141-147 7 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Monocytes
Atherosclerosis
In Vitro Techniques
Enzyme Reactivators
Neural Networks (Computer)
Intra-Abdominal Fat
Adipose Tissue
Fats
Oils and fats

Authors’ reply

Alkhalili, E., Greenbaum, A., Luo, L., Rodriguez, R., Caldwell, K., Estrada, O. M., O’Neill, J., Nir, I. & Morris, K. T. 2017 In : Annals of Gastroenterology. 30, 4, p. 471 1 p.

Research output: Contribution to journalLetter

Automated detection and quantification of residual brain tumor using an interactive computer-aided detection scheme

Gaffney, K. P., Aghaei, F., Battiste, J. & Zheng, B. 2017 Medical Imaging 2017: Computer-Aided Diagnosis. SPIE, Vol. 10134, 101342I

Research output: Chapter in Book/Report/Conference proceedingConference contribution

tumors
Residual Neoplasm
Brain Neoplasms
Contraception Behavior
Tumors
Lung Neoplasms
Learning
Area Under Curve
Lung
Bayesian networks

Balance the nodule shape and surroundings: A new multichannel image based convolutional neural network scheme on lung nodule diagnosis

Sun, W., Zheng, B., Huang, X. & Qian, W. 2017 Medical Imaging 2017: Computer-Aided Diagnosis. SPIE, Vol. 10134, 101343L

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Area Under Curve
Lung
nodules
Benzo(a)pyrene
Neural networks

Barriers and Strategies Related to Qualitative Research on Genetic Ancestry Testing in Indigenous Communities

Blanchard, J., Tallbull, G., Wolpert, C., Powell, J., Foster, M. & Royal, C. Apr 1 2017 In : Journal of Empirical Research on Human Research Ethics.

Research output: Contribution to journalArticle

genetics
Qualitative Research
Genetic Testing
Genetic Research
perception